ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

19013

Symbol:

Ppara

Full Name:

peroxisome proliferator activated receptor alpha

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E2|15 48.8 cM

Physical Location:

85566205-85633248 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5465 Symbol (Name): PPARA (peroxisome proliferator-activated receptor alpha)

Ortholog Status:

The human GeneID 5465 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011144.6	NP_035274.2	NC_000081.5 range: 85566205..85633248

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (10377439)
GO:0003677	DNA binding	Molecular Function	IDA (12015306\|15237213)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IDA (16271724)
GO:0016563	transcription activator activity	Molecular Function	IDA (8041794)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046982	protein heterodimerization activity	Molecular Function	TAS (16271724)
GO:0005515	protein binding	Molecular Function	ISS (11891224)
GO:0003700	transcription factor activity	Molecular Function	IMP (16271724)
GO:0005515	protein binding	Molecular Function	IPI (15870285)
GO:0003707	steroid hormone receptor activity	Molecular Function	TAS (10377439)
GO:0004879	ligand-dependent nuclear receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IDA (12802337)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (8041794)
GO:0045941	positive regulation of transcription	Biological Process	IMP (15007068)
GO:0019217	regulation of fatty acid metabolic process	Biological Process	IMP (9488698)
GO:0008544	epidermis development	Biological Process	IMP (12485431)
GO:0006631	fatty acid metabolic process	Biological Process	TAS (10377439)
GO:0006631	fatty acid metabolic process	Biological Process	IMP (15007068)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	TAS (10377439)
GO:0006350	transcription	Biological Process	IEA
GO:0006006	glucose metabolic process	Biological Process	TAS (10377439)
GO:0006629	lipid metabolic process	Biological Process	TAS (10377439)