ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PPARA

Full Name:

peroxisome proliferator-activated receptor alpha

Alias:

MGC2237|MGC2452|NR1C1|PPAR|hPPAR

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

22q12-q13.1|22q13.31

Physical Location:

44925162-45018316 on NC_000022.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 19013 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PPARA

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	TAS (16271724)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0008144	drug binding	Molecular Function	IDA (9113987)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0004879	ligand-dependent nuclear receptor activity	Molecular Function	IEA
GO:0003707	steroid hormone receptor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12039952\|16554032)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0032000	positive regulation of fatty acid beta-oxidation	Biological Process	TAS (16271724)
GO:0015908	fatty acid transport	Biological Process	TAS (16271724)
GO:0006350	transcription	Biological Process	IEA
GO:0006631	fatty acid metabolic process	Biological Process	TAS (10377439)
GO:0006629	lipid metabolic process	Biological Process	TAS (7684926\|9792666)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS (7684926)