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Gene Information
Gene ID:191575
Full Name:expressed in non-metastatic cells 1
Organism:Rattus norvegicus (Rat)
Genetic Location:10q26
Physical Location:82591704-82601074 on NC_005109.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 4830    Symbol (Name): NME1 (non-metastatic cells 1, protein (NM23A) expressed in)
Ortholog Status:The human GeneID 4830 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:191575
Fold Change:1.385
P Value:0.0155
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_138548.1NP_612557.1NC_005109.2 range: 82591704..82601074, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005625soluble fractionCellular ComponentISS
GO:0005634nucleusCellular ComponentIEA
GO:0005792microsomeCellular ComponentISS
GO:0005813centrosomeCellular ComponentIDA (11139339)
GO:0016301kinase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0043015gamma-tubulin bindingMolecular FunctionIDA (11139339)
GO:0005525GTP bindingMolecular FunctionISS
GO:0005524ATP bindingMolecular FunctionISS
GO:0005524ATP bindingMolecular FunctionIEA
GO:0000287magnesium ion bindingMolecular FunctionISS
GO:0000287magnesium ion bindingMolecular FunctionIEA
GO:0004550nucleoside diphosphate kinase activityMolecular FunctionIDA (11139339)
GO:0004550nucleoside diphosphate kinase activityMolecular FunctionIEA
GO:0004550nucleoside diphosphate kinase activityMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionIPI
GO:0005515protein bindingMolecular FunctionISS
GO:0004536deoxyribonuclease activityMolecular FunctionISS
GO:0043388positive regulation of DNA bindingBiological ProcessISS
GO:0030879mammary gland developmentBiological ProcessISS
GO:0009117nucleotide metabolic processBiological ProcessIEA
GO:0007595lactationBiological ProcessISS
GO:0006241CTP biosynthetic processBiological ProcessIEA
GO:0006228UTP biosynthetic processBiological ProcessIEA
GO:0006183GTP biosynthetic processBiological ProcessIEA
GO:0006165nucleoside diphosphate phosphorylationBiological ProcessIDA (11139339)
GO:0050679positive regulation of epithelial cell proliferationBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:191575