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Dataset Description
  • Dataset Name: 15846778
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 43
  • Tissue: Frontal cortex
  • Phenotype: Alcohol-preferring, alcohol-nonpreferring
  • Publication: Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
  • Dataset Summary: DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.

    Gene list of this dataset (43 genes)
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    25232Tyro3TYRO3 protein tyrosine kinase 33q36.125232 
    25205Il6stinterleukin 6 signal transducer2q14-q1625205 
    25701Mxi1Max interacting protein 11q5525701 
    25558Stxbp1syntaxin binding protein 13p1125558 
    24681Prkccprotein kinase C, gamma1q1224681 
    25550Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 11q5225550 
    64680Crhr2corticotropin releasing hormone receptor 24q2464680 
    117282Hnrpkheterogeneous nuclear ribonucleoprotein K17p14117282 
    116470Stx1asyntaxin 1A (brain)12q12116470 
    56080Atp5h-ps1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d, pseudogene 15q3656080 
    29598Atp2b1ATPase, Ca++ transporting, plasma membrane 17q1329598 
    29290Adora1adenosine A1 receptor13q1329290 
    81802Stx3syntaxin 31q4381802 
    25125Stat3signal transducer and activator of transcription 310q32.125125 
    191575Nme1expressed in non-metastatic cells 110q26191575 
    24888Bcl2l1Bcl2-like 13q41.224888 
    60661MaxMax protein6q2460661 
    29358Npy1rneuropeptide Y receptor Y116p1429358 
    25652Ptgfrprostaglandin F receptor2q4525652 
    81647Atf2activating transcription factor 23q2381647 
    24330Egr1early growth response 118q24330 
    25669Cpecarboxypeptidase E16p1325669 
    24245Camk2bcalcium/calmodulin-dependent protein kinase II, beta14q2124245 
    257648Cacna1bcalcium channel, voltage-dependent, N type, alpha 1B subunit3p13257648 
    25469Kcna4potassium voltage-gated channel, shaker-related subfamily, member 43q3325469 
    116635Scg3secretogranin III8q24116635 
    29753Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide10q2429753 
    25716Syt1synaptotagmin I7q2125716 
    24380Gad2glutamic acid decarboxylase 217q12.324380 
    24766Scn2a1sodium channel, voltage-gated, type II, alpha 13q2424766 
    25073Scarb1scavenger receptor class B, member 112q15-q1625073 
    81754Rab1RAB1, member RAS oncogene family14q2281754 
    24191Aldocaldolase C-24191 
    29689Gabrdgamma-aminobutyric acid (GABA-A) receptor, subunit delta5q3629689 
    50686Gsk3aglycogen synthase kinase 3 alpha1q2150686 
    65158Rab2aRAB2A, member RAS oncogene family5q1365158 
    116554Mapk8mitogen-activated protein kinase 816p16116554 
    81812Thrathyroid hormone receptor alpha10q3181812 
    81736Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1052q4381736 
    25293Aqp4aquaporin 418p1325293 
    29431Pak1p21 (CDKN1A)-activated kinase 11q3229431 
    25049Atxn1ataxin 117p1325049 
    25358Timp3tissue inhibitor of metalloproteinase 37q1325358