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Gene Information
Gene ID:25701
Full Name:Max interacting protein 1
Organism:Rattus norvegicus (Rat)
Genetic Location:1q55
Physical Location:259219583-259259978 on NC_005100.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 4601    Symbol (Name): MXI1 (MAX interactor 1)
Ortholog Status:The human GeneID 4601 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:25701
Fold Change:1.814
P Value:0.009
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_013160.2NP_037292.2NC_005100.2 range: 259219583..259259978, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIDA (9130602)
GO:0005634nucleusCellular ComponentIDA (9130602|11498788)
GO:0005634nucleusCellular ComponentIEA
GO:0005634nucleusCellular ComponentISS
GO:0016564transcription repressor activityMolecular FunctionTAS (10849326)
GO:0016564transcription repressor activityMolecular FunctionISS
GO:0030528transcription regulator activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0003677DNA bindingMolecular FunctionIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIDA (11498788)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:25701