| Gene Information |
| Gene ID: | | 25701 |
| Symbol: | | Mxi1 |
| Full Name: | | Max interacting protein 1 |
| Alias: | | MXI-WR |
| Organism: | | Rattus norvegicus (Rat) |
| Chromosome: | | 1 |
| Genetic Location: | | 1q55 |
| Physical Location: | | 259219583-259259978 on NC_005100.2, complement |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 4601 Symbol (Name): MXI1 (MAX interactor 1) |
| Ortholog Status: | | The human GeneID 4601 is not in current human dataset. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | 25701 | | Fold Change: | | 1.814 | | P Value: | | 0.009 | | Note: | | Fold change is average ratio of AA to ANA. |
| | Dataset Information | | Name: | | 15846778 | | Method: | | Microarray | | Tissue: | | Frontal cortex | | Phenotype: | | Alcohol-preferring, alcohol-nonpreferring | | Publication: | | Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed | | Summary: | | DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005737 | cytoplasm | Cellular Component | IDA (9130602) | |
| GO:0005634 | nucleus | Cellular Component | IDA (9130602|11498788) | |
| GO:0005634 | nucleus | Cellular Component | IEA | |
| GO:0005634 | nucleus | Cellular Component | ISS | |
| GO:0016564 | transcription repressor activity | Molecular Function | TAS (10849326) | |
| GO:0016564 | transcription repressor activity | Molecular Function | ISS | |
| GO:0030528 | transcription regulator activity | Molecular Function | IEA | |
| GO:0005515 | protein binding | Molecular Function | ISS | |
| GO:0003677 | DNA binding | Molecular Function | IEA | |
| GO:0006355 | regulation of transcription, DNA-dependent | Biological Process | IDA (11498788) | |
| GO:0006355 | regulation of transcription, DNA-dependent | Biological Process | IEA | |
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | Biological Process | ISS | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 25701 |
| RGD: | | 3128 |
| Ensembl: | | ENSRNOG00000031846 |
| dbSNP: | | Mxi1 |
