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Gene Information
Gene ID:25232
Full Name:TYRO3 protein tyrosine kinase 3
Organism:Rattus norvegicus (Rat)
Genetic Location:3q36.1
Physical Location:106309670-106328606 on NC_005102.2
Gene Type:protein-coding
Human Ortholog:GeneID: 7301    Symbol (Name): TYRO3 (TYRO3 protein tyrosine kinase)
Ortholog Status:The human GeneID 7301 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:25232
Fold Change:2.206
P Value:<0.001
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017092.1NP_058788.1NC_005102.2 range: 106309670..106328606
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0043548phosphoinositide 3-kinase bindingMolecular FunctionIPI (10627473)
GO:0005524ATP bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0004872receptor activityMolecular FunctionIEA
GO:0004714transmembrane receptor protein tyrosine kinase activityMolecular FunctionIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIDA (10627473)
GO:0007155cell adhesionBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:25232