ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Max

Full Name:

Max protein

Alias:

MGC124611

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

6q24

Physical Location:

99529904-99553850 on NC_005105.2, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4149 Symbol (Name): MAX (MYC associated factor X)

Ortholog Status:

The human GeneID 4149 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		60661
Fold Change:		1.371
P Value:		0.045
Note:		Fold change is average ratio of AA to ANA.

Dataset Information

Name:		15846778
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:		DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_022210.1	NP_071546.1	NC_005105.2 range: 99529904..99553850, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (9130602)
GO:0003677	DNA binding	Molecular Function	ISS
GO:0003700	transcription factor activity	Molecular Function	IMP (17341548)
GO:0005515	protein binding	Molecular Function	ISS
GO:0043565	sequence-specific DNA binding	Molecular Function	IDA (17341548)
GO:0046982	protein heterodimerization activity	Molecular Function	IPI (17341548)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IMP (17341548)
GO:0045449	regulation of transcription	Biological Process	ISS