ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Aldoc

Full Name:

aldolase C

Alias:

ALDCAA|F16dip7|RATALDCAA

Organism:

Rattus norvegicus (Rat)

Chromosome:

Physical Location:

64308825-64312414 on NC_005109.2, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 230 Symbol (Name): ALDOC (aldolase C, fructose-bisphosphate)

Ortholog Status:

The human GeneID 230 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		24191
Fold Change:		0.68
P Value:		0.0065
Note:		Fold change is average ratio of AA to ANA.

Dataset Information

Name:		15846778
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:		DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_012497.1	NP_036629.1	NC_005109.2 range: 64308825..64312414, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	ISS
GO:0004332	fructose-bisphosphate aldolase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	ISS
GO:0016829	lyase activity	Molecular Function	IEA
GO:0006096	glycolysis	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA