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Gene Information
Gene ID:25558
Full Name:syntaxin binding protein 1
Organism:Rattus norvegicus (Rat)
Genetic Location:3p11
Physical Location:11762104-11825530 on NC_005102.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 6812    Symbol (Name): STXBP1 (syntaxin binding protein 1)
Ortholog Status:The human GeneID 6812 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:25558
Fold Change:1.8
P Value:<0.001
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_013038.3NP_037170.1NC_005102.2 range: 11762104..11825530, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentISS
GO:0005829cytosolCellular ComponentTAS (12093152)
GO:0005886plasma membraneCellular ComponentIDA (12093152)
GO:0005515protein bindingMolecular FunctionIDA (12963086)
GO:0019905syntaxin bindingMolecular FunctionIDA (12506202)
GO:0017075syntaxin-1 bindingMolecular FunctionIDA (12093152)
GO:0047485protein N-terminus bindingMolecular FunctionIPI (8247129)
GO:0005515protein bindingMolecular FunctionISS
GO:0007412axon target recognitionBiological ProcessISS
GO:0016188synaptic vesicle maturationBiological ProcessISS
GO:0006944membrane fusionBiological ProcessIPI (12506202)
Other Database Cross Links
NCBI Entrez Gene:25558