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Gene Information
Gene ID:50686
Full Name:glycogen synthase kinase 3 alpha
Organism:Rattus norvegicus (Rat)
Genetic Location:1q21
Physical Location:80505516-80514137 on NC_005100.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2931    Symbol (Name): GSK3A (glycogen synthase kinase 3 alpha)
Ortholog Status:The human GeneID 2931 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:50686
Fold Change:0.642
P Value:0.021
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017344.1NP_059040.1NC_005100.2 range: 80505516..80514137, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0004696glycogen synthase kinase 3 activityMolecular FunctionNAS (2164470)
GO:0004674protein serine/threonine kinase activityMolecular FunctionIEA
GO:0004674protein serine/threonine kinase activityMolecular FunctionIDA (2164470)
GO:0004672protein kinase activityMolecular FunctionISS
GO:0050321tau-protein kinase activityMolecular FunctionIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessISS
GO:0007165signal transductionBiological ProcessNAS (2164470)
Other Database Cross Links
NCBI Entrez Gene:50686