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Gene Information
Gene ID:29753
Full Name:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Organism:Rattus norvegicus (Rat)
Genetic Location:10q24
Physical Location:63072127-63109832 on NC_005109.2
Gene Type:protein-coding
Human Ortholog:GeneID: 7531    Symbol (Name): YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide)
Ortholog Status:The human GeneID 7531 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:29753
Fold Change:0.855
P Value:0.019
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_031603.1NP_113791.1NC_005109.2 range: 63072127..63109832
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0042470melanosomeCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005739mitochondrionCellular ComponentISS
GO:0019904protein domain specific bindingMolecular FunctionISS
GO:0019904protein domain specific bindingMolecular FunctionIEA
GO:0019899enzyme bindingMolecular FunctionISS
GO:0019899enzyme bindingMolecular FunctionIPI (8694795)
GO:0008426protein kinase C inhibitor activityMolecular FunctionTAS (8694795)
GO:0005515protein bindingMolecular FunctionISS
GO:0007165signal transductionBiological ProcessTAS (8694795)
GO:0006605protein targetingBiological ProcessISS
GO:0021766hippocampus developmentBiological ProcessISS
GO:0021987cerebral cortex developmentBiological ProcessISS
GO:0035308negative regulation of protein amino acid dephosphorylationBiological ProcessISS
GO:0001764neuron migrationBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:29753