Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:25073
Symbol:Scarb1
Full Name:scavenger receptor class B, member 1
Alias:Cd36l1|SR-B1|Srb1
Organism:Rattus norvegicus (Rat)
Chromosome:12
Genetic Location:12q15-q16
Physical Location:32390182-32457660 on NC_005111.2
Gene Type:protein-coding
Human Ortholog:GeneID: 949    Symbol (Name): SCARB1 (scavenger receptor class B, member 1)
Ortholog Status:The human GeneID 949 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:25073
Fold Change:0.691
P Value:0.033
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Name:15846778
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_031541.1NP_113729.1NC_005111.2 range: 32390182..32457660
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000299integral to membrane of membrane fractionCellular ComponentISS
GO:0009986cell surfaceCellular ComponentIDA (11882321)
GO:0016020membraneCellular ComponentIEA
GO:0031528microvillus membraneCellular ComponentIMP (14657200)
GO:0005901caveolaCellular ComponentISS
GO:0005887integral to plasma membraneCellular ComponentISS
GO:0005737cytoplasmCellular ComponentIDA (11882321)
GO:0005515protein bindingMolecular FunctionISS
GO:0005319lipid transporter activityMolecular FunctionTAS (9177301|9421400|10026214|12016218|12746305)
GO:0004872receptor activityMolecular FunctionIEA
GO:0001786phosphatidylserine bindingMolecular FunctionTAS (10026214)
GO:0001786phosphatidylserine bindingMolecular FunctionIDA (12016218)
GO:0008035high-density lipoprotein bindingMolecular FunctionISS
GO:0043534blood vessel endothelial cell migrationBiological ProcessISS
GO:0050764regulation of phagocytosisBiological ProcessIDA (12016218)
GO:0030301cholesterol transportBiological ProcessISS
GO:0007155cell adhesionBiological ProcessIEA
GO:0006910phagocytosis, recognitionBiological ProcessIMP (12016218)
GO:0006869lipid transportBiological ProcessIMP (12032160)
GO:0006707cholesterol catabolic processBiological ProcessISS
GO:0006702androgen biosynthetic processBiological ProcessIDA (12746305)
GO:0006694steroid biosynthetic processBiological ProcessTAS (9421400|10026214|12016218|12746305)
GO:0001935endothelial cell proliferationBiological ProcessISS
GO:0050764regulation of phagocytosisBiological ProcessTAS (10026214)
Other Database Cross Links
NCBI Entrez Gene:25073
RGD:2302
Ensembl:ENSRNOG00000000981
dbSNP:Scarb1