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Gene Information
Gene ID:29358
Symbol:Npy1r
Full Name:neuropeptide Y receptor Y1
Alias:MGC109393|NPY-1
Organism:Rattus norvegicus (Rat)
Chromosome:16
Genetic Location:16p14
Physical Location:24747182-24756506 on NC_005115.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 4886    Symbol (Name): NPY1R (neuropeptide Y receptor Y1)
Ortholog Status:The human GeneID 4886 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:29358
Fold Change:1.254
P Value:0.0305
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Name:15846778
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001013032.1NP_001013050.1NC_005115.2 range: 24747182..24756506, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentIEA
GO:0008021synaptic vesicleCellular ComponentIDA (11891789)
GO:0030424axonCellular ComponentIDA (11891789)
GO:0005886plasma membraneCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentIDA (11891789)
GO:0005829cytosolCellular ComponentIDA (11891789)
GO:0004872receptor activityMolecular FunctionIEA
GO:0001601peptide YY receptor activityMolecular FunctionIEA
GO:0001601peptide YY receptor activityMolecular FunctionISS
GO:0001584rhodopsin-like receptor activityMolecular FunctionIEA
GO:0001602pancreatic polypeptide receptor activityMolecular FunctionIEA
GO:0001602pancreatic polypeptide receptor activityMolecular FunctionISS
GO:0003674molecular_functionMolecular FunctionND
GO:0005515protein bindingMolecular FunctionISS
GO:0004983neuropeptide Y receptor activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0004983neuropeptide Y receptor activityMolecular FunctionISS
GO:0019233sensory perception of painBiological ProcessIEA
GO:0019233sensory perception of painBiological ProcessIMP (15099684)
GO:0019233sensory perception of painBiological ProcessISS
GO:0030432peristalsisBiological ProcessIMP
GO:0032355response to estradiol stimulusBiological ProcessIEP (14726443)
GO:0040014regulation of multicellular organism growthBiological ProcessIEA
GO:0045907positive regulation of vasoconstrictionBiological ProcessIMP (9802404)
GO:0046888negative regulation of hormone secretionBiological ProcessIMP (10464394)
GO:0040014regulation of multicellular organism growthBiological ProcessISS
GO:0008217regulation of blood pressureBiological ProcessISS
GO:0008217regulation of blood pressureBiological ProcessIEA
GO:0006006glucose metabolic processBiological ProcessIEA
GO:0006006glucose metabolic processBiological ProcessISS
GO:0007165signal transductionBiological ProcessIEA
GO:0007186G-protein coupled receptor protein signaling pathwayBiological ProcessIEA
GO:0007218neuropeptide signaling pathwayBiological ProcessIEA
GO:0007626locomotory behaviorBiological ProcessIEA
GO:0007626locomotory behaviorBiological ProcessISS
GO:0007631feeding behaviorBiological ProcessIEA
GO:0007631feeding behaviorBiological ProcessISS
GO:0007631feeding behaviorBiological ProcessISS
GO:0051481reduction of cytosolic calcium ion concentrationBiological ProcessIMP (17143304)
Other Database Cross Links
NCBI Entrez Gene:29358
RGD:3198
Ensembl:ENSRNOG00000014149
dbSNP:Npy1r