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Gene Information
Gene ID:29689
Full Name:gamma-aminobutyric acid (GABA-A) receptor, subunit delta
Organism:Rattus norvegicus (Rat)
Genetic Location:5q36
Physical Location:172203055-172214963 on NC_005104.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2563    Symbol (Name): GABRD (gamma-aminobutyric acid (GABA) A receptor, delta)
Ortholog Status:The human GeneID 2563 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:29689
Fold Change:0.644
P Value:0.0195
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017289.1NP_058985.1NC_005104.2 range: 172203055..172214963, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045211postsynaptic membraneCellular ComponentIEA
GO:0045202synapseCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0031404chloride ion bindingMolecular FunctionIEA
GO:0030594neurotransmitter receptor activityMolecular FunctionIEA
GO:0004890GABA-A receptor activityMolecular FunctionIDA (12356876)
GO:0005254chloride channel activityMolecular FunctionIEA
GO:0005230extracellular ligand-gated ion channel activityMolecular FunctionIEA
GO:0005216ion channel activityMolecular FunctionIEA
GO:0004890GABA-A receptor activityMolecular FunctionIEA
GO:0006811ion transportBiological ProcessIEA
GO:0007268synaptic transmissionBiological ProcessIDA (12356876)
Other Database Cross Links
NCBI Entrez Gene:29689