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Gene Information
Gene ID:25049
Full Name:ataxin 1
Organism:Rattus norvegicus (Rat)
Genetic Location:17p13
Physical Location:24719051-25138269 on NC_005116.2
Gene Type:protein-coding
Human Ortholog:GeneID: 6310    Symbol (Name): ATXN1 (ataxin 1)
Ortholog Status:The human GeneID 6310 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:25049
Fold Change:0.509
P Value:0.009
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_012726.2NP_036858.1NC_005116.2 range: 24719051..25138269
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0042272nuclear RNA export factor complexCellular ComponentISS
GO:0016363nuclear matrixCellular ComponentISS
GO:0042405nuclear inclusion bodyCellular ComponentISS
GO:0005737cytoplasmCellular ComponentISS
GO:0005654nucleoplasmCellular ComponentISS
GO:0005634nucleusCellular ComponentISS
GO:0005575cellular_componentCellular ComponentND
GO:0042272nuclear RNA export factor complexCellular ComponentISS
GO:0016564transcription repressor activityMolecular FunctionISS
GO:0034046poly(rG) bindingMolecular FunctionISS
GO:0042802identical protein bindingMolecular FunctionIEA
GO:0042802identical protein bindingMolecular FunctionISS
GO:0043621protein self-associationMolecular FunctionISS
GO:0003674molecular_functionMolecular FunctionND
GO:0008266poly(U) bindingMolecular FunctionISS
GO:0008022protein C-terminus bindingMolecular FunctionISS
GO:0003723RNA bindingMolecular FunctionISS
GO:0003723RNA bindingMolecular FunctionIEA
GO:0060079regulation of excitatory postsynaptic membrane potentialBiological ProcessIEA
GO:0051168nuclear exportBiological ProcessISS
GO:0016481negative regulation of transcriptionBiological ProcessISS
GO:0008542visual learningBiological ProcessISS
GO:0008542visual learningBiological ProcessIEA
GO:0008344adult locomotory behaviorBiological ProcessISS
GO:0008344adult locomotory behaviorBiological ProcessIEA
GO:0008150biological_processBiological ProcessND
GO:0060079regulation of excitatory postsynaptic membrane potentialBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:25049