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Gene Information
Gene ID:81647
Full Name:activating transcription factor 2
Organism:Rattus norvegicus (Rat)
Genetic Location:3q23
Physical Location:56427235-56496472 on NC_005102.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 1386    Symbol (Name): ATF2 (activating transcription factor 2)
Ortholog Status:The human GeneID 1386 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:81647
Fold Change:1.181
P Value:0.0365
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_031018.1NP_112280.1NC_005102.2 range: 56427235..56496472, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005624membrane fractionCellular ComponentISS
GO:0003677DNA bindingMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionISS
GO:0016563transcription activator activityMolecular FunctionIDA (12196528)
GO:0043565sequence-specific DNA bindingMolecular FunctionIDA (17428807)
GO:0046982protein heterodimerization activityMolecular FunctionIPI (17428807)
GO:0007399nervous system developmentBiological ProcessNAS (12196528)
GO:0042423catecholamine biosynthetic processBiological ProcessIPI (12196528)
Other Database Cross Links
NCBI Entrez Gene:81647