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Gene Information
Gene ID:24681
Full Name:protein kinase C, gamma
Organism:Rattus norvegicus (Rat)
Genetic Location:1q12
Physical Location:64145748-64172711 on NC_005100.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 5582    Symbol (Name): PRKCG (protein kinase C, gamma)
Ortholog Status:The human GeneID 5582 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:24681
Fold Change:1.655
P Value:0.001
Note:Fold change is average ratio of AA to ANA.
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Worst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
Summary:DNA macroarrays were used to probe for differences in normative cortical gene expression between rat strains genetically selected for alcohol selfadministration preference, AA (Alko, alcohol) and P (Indiana, preferring), or avoidance, ANA (Alko, nonalcohol) and NP (Indiana, nonpreferring). Among 1,176 genes studied, six demonstrated confirmable, differential expression following comparison of ethanol-naive AA and ANA rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_012628.1NP_036760.1NC_005100.2 range: 64145748..64172711, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0030425dendriteCellular ComponentISS
GO:0005829cytosolCellular ComponentIDA (14688616)
GO:0005737cytoplasmCellular ComponentISS
GO:0005737cytoplasmCellular ComponentIEA
GO:0005634nucleusCellular ComponentISS
GO:0005634nucleusCellular ComponentIEA
GO:0030425dendriteCellular ComponentIEA
GO:0019717synaptosomeCellular ComponentIDA (14688616)
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0004697protein kinase C activityMolecular FunctionIDA (11507002)
GO:0004697protein kinase C activityMolecular FunctionIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0019992diacylglycerol bindingMolecular FunctionIEA
GO:0032425positive regulation of mismatch repairBiological ProcessISS
GO:0031397negative regulation of protein ubiquitinationBiological ProcessIEA
GO:0031397negative regulation of protein ubiquitinationBiological ProcessISS
GO:0032425positive regulation of mismatch repairBiological ProcessIEA
GO:0042177negative regulation of protein catabolic processBiological ProcessIEA
GO:0007635chemosensory behaviorBiological ProcessISS
GO:0007635chemosensory behaviorBiological ProcessIEA
GO:0007611learning and/or memoryBiological ProcessIEP (12000125)
GO:0007268synaptic transmissionBiological ProcessNAS (14688616)
GO:0007242intracellular signaling cascadeBiological ProcessNAS (11507002)
GO:0007242intracellular signaling cascadeBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
GO:0042177negative regulation of protein catabolic processBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:24681