ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Polr2a

Full Name:

polymerase (RNA) II (DNA directed) polypeptide A

Alias:

220kDa|Rpo2-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1-C|11 37.0 cM

Physical Location:

69547911-69571724 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5430 Symbol (Name): POLR2A (polymerase (RNA) II (DNA directed) polypeptide A, 220kDa)

Ortholog Status:

The human GeneID 5430 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore4	Alcohol-induced Loss of Righting Reflex	11		36-42 (cM)	6.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009089.2	NP_033115.1	NC_000077.5 range: 69547911..69571724, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005730	nucleolus	Cellular Component	ISS (16109376)
GO:0005634	nucleus	Cellular Component	ISS (14580349\|16109376)
GO:0005665	DNA-directed RNA polymerase II, core complex	Cellular Component	IEA
GO:0016779	nucleotidyltransferase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (14612417)
GO:0003899	DNA-directed RNA polymerase activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IDA (15601870)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	IEA