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Gene Information
Gene ID:2030
Symbol:SLC29A1
Full Name:solute carrier family 29 (nucleoside transporters), member 1
Alias:ENT1|MGC1465|MGC3778
Organism:Homo sapiens (Human)
Chromosome:6
Genetic Location:6p21.2-p21.1
Physical Location:44295219-44309865 on NC_000006.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:SLC29A1
Dataset Information
Name:18477577
Method:Addiction array gene list
Publication:Hodgkinson et al. Alcohol Alcohol. (2008) Addictions Biology: Haplotype-Based Analysis for 130 Candidate Genes on a Single Array. PubMed
Summary:To develop a panel of markers able to extract full haplotype information for candidate genes in alcoholism, other addictions and disorders of mood and anxiety. Methods: A total of 130 genes were haplotype tagged and genotyped in 7 case/control populations and 51 reference populations using Illumina GoldenGate SNP genotyping technology, determining haplotype coverage. The 130 candidate genes were selected on the basis of their roles in functional domains important in the addictions and in the related phenotypes of anxiety and depression. The candidate genes included a limited number involved in the pharmacokinetic domain (e.g. several genes in the ADH gene cluster, and ALDH genes). The majority of the genes represent the domains of vulnerability to drug use and pharmacodynamic response. These include dopamine, serotonin, glutamine, GABA, and opioid neurotransmitter genes, signaling genes, and genes modulating stress resiliency and behavioral dyscontrol domains. There is a high degree of overlap between functional gene categories because of pleiotropic actions of molecules on behavior.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001078174.1NP_001071642.1NC_000006.10 range: 44295219..44309865
NM_001078175.1NP_001071643.1NC_000006.10 range: 44295219..44309865
NM_001078176.1NP_001071644.1NC_000006.10 range: 44295219..44309865
NM_001078177.1NP_001071645.1NC_000006.10 range: 44295219..44309865
NM_004955.2NP_004946.1NC_000006.10 range: 44295219..44309865
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005624membrane fractionCellular ComponentTAS (8986748)
GO:0005887integral to plasma membraneCellular ComponentTAS (8986748)
GO:0016020membraneCellular ComponentIEA
GO:0005337nucleoside transmembrane transporter activityMolecular FunctionTAS (8986748)
GO:0005515protein bindingMolecular FunctionIPI (14667819)
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic processBiological ProcessTAS (8986748)
GO:0006810transportBiological ProcessIEA
GO:0015858nucleoside transportBiological ProcessTAS (8986748)
Other Database Cross Links
NCBI Entrez Gene:2030
HGNC:11003
Ensembl:ENSG00000112759
MIM:602193
HPRD:03724
HuGE Navigator:2030
dbSNP:SLC29A1
GeneCard:SLC29A1
AceView:SLC29A1