ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Siah1a

Full Name:

seven in absentia 1A

Alias:

AA982064|AI853500|Sinh1a

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 C3|8 38.5 cM

Physical Location:

89247905-89269832 on NC_000074.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6477 Symbol (Name): SIAH1 (seven in absentia homolog 1 (Drosophila))

Ortholog Status:

The human GeneID 6477 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009172.1	NP_033198.1	NC_000074.5 range: 89247905..89269832, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	TAS (11884614)
GO:0016874	ligase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12646221)
GO:0006915	apoptosis	Biological Process	IEA
GO:0040014	regulation of multicellular organism growth	Biological Process	IMP (11884614)
GO:0030154	cell differentiation	Biological Process	IEA
GO:0009791	post-embryonic development	Biological Process	IMP (11884614)
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IEA
GO:0007283	spermatogenesis	Biological Process	IMP (11884614)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0007049	cell cycle	Biological Process	IEA
GO:0007141	male meiosis I	Biological Process	IMP (11884614)