ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Sparc

Full Name:

secreted acidic cysteine rich glycoprotein

Alias:

AA517111|BM-40

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1|11 29.9 cM

Physical Location:

55208002-55233367 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6678 Symbol (Name): SPARC (secreted protein, acidic, cysteine-rich (osteonectin))

Ortholog Status:

The human GeneID 6678 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009242.4	NP_033268.1	NC_000077.5 range: 55208002..55233367, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0005604	basement membrane	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005507	copper ion binding	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	NAS (15609325)