ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

213

Symbol:

ALB

Full Name:

albumin

Alias:

DKFZp779N1935|PRO0883|PRO0903|PRO1341

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

4q11-q13

Physical Location:

74488869-74505995 on NC_000004.10

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 24186 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ALB

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

Original ID	No. of Publications	Phenotype
ALB	1	Alcoholism

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000477.4	NP_000468.1	NC_000004.10 range: 74488869..74505995

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0031093	platelet alpha granule lumen	Cellular Component	EXP (6457647)
GO:0043234	protein complex	Cellular Component	IDA (16283771)
GO:0005615	extracellular space	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	NAS (14718574)
GO:0005576	extracellular region	Cellular Component	EXP (6457647\|7557095\|8132774\|11159893)
GO:0005515	protein binding	Molecular Function	IPI (16099937)
GO:0030170	pyridoxal phosphate binding	Molecular Function	IDA (16201370)
GO:0019825	oxygen binding	Molecular Function	IDA (16283771)
GO:0016209	antioxidant activity	Molecular Function	NAS (14726550)
GO:0015643	toxin binding	Molecular Function	IDA (16169013)
GO:0003677	DNA binding	Molecular Function	IDA (16405401)
GO:0008144	drug binding	Molecular Function	NAS (10940303)
GO:0008144	drug binding	Molecular Function	IDA (16169013\|16307046\|16413734\|16413740)
GO:0005504	fatty acid binding	Molecular Function	IDA (16289007\|16413837)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005504	fatty acid binding	Molecular Function	NAS (9731778)
GO:0005507	copper ion binding	Molecular Function	NAS (14726550)
GO:0043066	negative regulation of apoptosis	Biological Process	IDA (16153637)
GO:0043072	negative regulation of non-apoptotic programmed cell death	Biological Process	NAS (14726550)
GO:0019836	hemolysis by symbiont of host red blood cells	Biological Process	IDA (16394536)
GO:0009267	cellular response to starvation	Biological Process	IDA (16245148)
GO:0006810	transport	Biological Process	TAS (12617161)
GO:0006810	transport	Biological Process	IEA
GO:0051659	maintenance of mitochondrion localization	Biological Process	IDA (16153637)