ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mll1

Full Name:

myeloid/lymphoid or mixed-lineage leukemia 1

Alias:

6430520K01|ALL-1|All1|Cxxc7|HRX|HTRX1|KIAA4050|KMT2A|Mll|mKIAA4050

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 A5.2

Physical Location:

44611437-44689356 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4297 Symbol (Name): MLL (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila))

Ortholog Status:

The human GeneID 4297 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001081049.1	NP_001074518.1	NC_000075.5 range: 44611437..44689356, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0044428	nuclear part	Cellular Component	IDA (16618927)
GO:0005634	nucleus	Cellular Component	IDA (11555636)
GO:0005634	nucleus	Cellular Component	ISO
GO:0003677	DNA binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0003682	chromatin binding	Molecular Function	IDA (15640349)
GO:0005515	protein binding	Molecular Function	IPI (16618927)
GO:0006350	transcription	Biological Process	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (15640349)
GO:0035162	embryonic hemopoiesis	Biological Process	IMP (9639506)
GO:0009952	anterior/posterior pattern formation	Biological Process	IMP (16618927)
GO:0009952	anterior/posterior pattern formation	Biological Process	IGI (15741318)
GO:0008285	negative regulation of cell proliferation	Biological Process	IMP (15640349)
GO:0006306	DNA methylation	Biological Process	IMP (16618927)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0051569	regulation of histone H3-K4 methylation	Biological Process	IMP (16618927)