ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MLL

Full Name:

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

Alias:

ALL-1|CXXC7|FLJ11783|HRX|HTRX1|KMT2A|MLL/GAS7|MLL1A|TRX1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q23

Physical Location:

117812414-117901145 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 214162 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MLL

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005933.2	NP_005924.2	NC_000011.8 range: 117812414..117901145

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (15640349)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0042803	protein homodimerization activity	Molecular Function	IDA (11313484)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005525	GTP binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	NAS (10821850)
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0003702	RNA polymerase II transcription factor activity	Molecular Function	TAS (10821850)
GO:0035162	embryonic hemopoiesis	Biological Process	TAS (15618964)
GO:0007049	cell cycle	Biological Process	IEA
GO:0006915	apoptosis	Biological Process	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0006461	protein complex assembly	Biological Process	IDA (15199122)
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS (10821850)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006310	DNA recombination	Biological Process	IEA
GO:0006281	DNA repair	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA