ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

22138

Symbol:

Ttn

Full Name:

titin

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 D|2 44.0 cM

Physical Location:

76542040-76820603 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7273 Symbol (Name): TTN (titin)

Ortholog Status:

The human GeneID 7273 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011652.3	NP_035782.3	NC_000068.6 range: 76542040..76820603, complement
NM_028004.2	NP_082280.2	NC_000068.6 range: 76542040..76820603, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0031674	I band	Cellular Component	IDA (16481394\|16702235)
GO:0031672	A band	Cellular Component	IDA (16481394\|16702235)
GO:0031430	M band	Cellular Component	IDA (15138196\|16702235)
GO:0030018	Z disc	Cellular Component	IDA (15138196\|16481394)
GO:0030017	sarcomere	Cellular Component	IDA (12651156)
GO:0005859	muscle myosin complex	Cellular Component	TAS (2129545)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (14741210\|15138196\|15967462)
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0005200	structural constituent of cytoskeleton	Molecular Function	TAS (8618961)
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005516	calmodulin binding	Molecular Function	IEA
GO:0045214	sarcomere organization	Biological Process	IMP (16702235)
GO:0045214	sarcomere organization	Biological Process	TAS (2129545)
GO:0055002	striated muscle cell development	Biological Process	IMP (16115818)
GO:0043056	forward locomotion	Biological Process	IMP (16115818)
GO:0007512	adult heart development	Biological Process	IMP (16702235)
GO:0006936	muscle contraction	Biological Process	IMP (16115818)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0003007	heart morphogenesis	Biological Process	IMP (16702235)
GO:0001701	in utero embryonic development	Biological Process	IMP (16702235)
GO:0055003	cardiac myofibril assembly	Biological Process	IMP (16702235)