ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

7273

Symbol:

TTN

Full Name:

titin

Alias:

CMD1G|CMH9|CMPD4|CONNECTIN|DKFZp451N061|EOMFC|FLJ26020|FLJ26409|FLJ32040|FLJ34413|FLJ39564|FLJ43066|HMERF|LGMD2J|TMD

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

2q31

Physical Location:

179098961-179380394 on NC_000002.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 22138 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TTN

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003319.3	NP_003310.3	NC_000002.10 range: 179098961..179380394, complement
NM_133378.3	NP_596869.3	NC_000002.10 range: 179098961..179380394, complement
NM_133379.2	NP_596870.2	NC_000002.10 range: 179098961..179380394, complement
NM_133432.2	NP_597676.2	NC_000002.10 range: 179098961..179380394, complement
NM_133437.2	NP_597681.2	NC_000002.10 range: 179098961..179380394, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0000794	condensed nuclear chromosome	Cellular Component	TAS (10481174)
GO:0005634	nucleus	Cellular Component	IEA
GO:0030018	Z disc	Cellular Component	TAS (8937992)
GO:0030018	Z disc	Cellular Component	IDA (9501083)
GO:0030017	sarcomere	Cellular Component	TAS (7569978)
GO:0005622	intracellular	Cellular Component	IEA
GO:0051393	alpha-actinin binding	Molecular Function	TAS (10481174)
GO:0008307	structural constituent of muscle	Molecular Function	TAS (7569978)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0017022	myosin binding	Molecular Function	TAS (11717165)
GO:0020037	heme binding	Molecular Function	IEA
GO:0042802	identical protein binding	Molecular Function	IPI (9804419)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0004601	peroxidase activity	Molecular Function	IEA
GO:0005089	Rho guanyl-nucleotide exchange factor activity	Molecular Function	IEA
GO:0005516	calmodulin binding	Molecular Function	TAS (10481174)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004197	cysteine-type endopeptidase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	TAS (9804419)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA (9804419)
GO:0030239	myofibril assembly	Biological Process	IMP (9804419)
GO:0035023	regulation of Rho protein signal transduction	Biological Process	IEA
GO:0046777	protein amino acid autophosphorylation	Biological Process	IMP (9804419)
GO:0005975	carbohydrate metabolic process	Biological Process	IEA
GO:0007067	mitosis	Biological Process	TAS (10481174)
GO:0006979	response to oxidative stress	Biological Process	IEA
GO:0006941	striated muscle contraction	Biological Process	TAS (7569978)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0006508	proteolysis	Biological Process	IEA