ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ube2m

Full Name:

ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)

Alias:

MGC25453|MGC37197|UBC12|Ubc-rs2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 A1|7 4.0 cM

Physical Location:

13620586-13623326 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9040 Symbol (Name): UBE2M (ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast))

Ortholog Status:

The human GeneID 9040 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Ube2m

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_145578.1	NP_663553.1	NC_000073.5 range: 13620586..13623326, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016874	ligase activity	Molecular Function	IEA
GO:0019787	small conjugating protein ligase activity	Molecular Function	IEA
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0043687	post-translational protein modification	Biological Process	IEA
GO:0051246	regulation of protein metabolic process	Biological Process	IEA