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Gene Information
Gene ID:22671
Symbol:Zfp179
Full Name:zinc finger protein 179
Alias:AI854096|R75574|ZNF179|bfp
Organism:Mus musculus (Mouse)
Chromosome:11
Genetic Location:11 B1.3|11 34.35 cM
Physical Location:61261943-61267387 on NC_000077.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 7732    Symbol (Name): ZNF179 (zinc finger protein 179)
Ortholog Status:The human GeneID 7732 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Zfp179
P Value:0.002
Note:Differentially expressed genes in brains of HAFT and LAFT mice. The P_value is the QTL P_value.
Dataset Information
Name:12805289
Method:Microarray and QTL
Tissue:Whole brain
Phenotype:Acute functional tolerance to ethanol
Publication:Tabakoff et al. J Neurosci. (2003) Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors. PubMed
Summary:We describe a novel approach that uses a combination of selective breeding, quantitative trait locus analysis, and DNA microarray technology to identify candidate genes for the complex phenotype of ethanol tolerance. Tolerance that develops during a single exposure to alcohol is defined as acute functional tolerance (AFT). Lines of mice to display high acute functional tolerance (HAFT mice) and low acute functional tolerance (LAFT mice) to the incoordinating effect of ethanol were used.
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Caws4/Alcw3Chronic Alcohol Withdrawal11 15-36 (cM)6.72.00E-07SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_009548.2NP_033574.2NC_000077.5 range: 61261943..61267387, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentRCA (12466851)
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:22671
MGI:
Ensembl:ENSMUSG00000010086
dbSNP:Zfp179
AceView:Zfp179