ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Zfp179

Full Name:

zinc finger protein 179

Alias:

AI854096|R75574|ZNF179|bfp

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1.3|11 34.35 cM

Physical Location:

61261943-61267387 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7732 Symbol (Name): ZNF179 (zinc finger protein 179)

Ortholog Status:

The human GeneID 7732 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Zfp179
P Value:		0.002
Note:		Differentially expressed genes in brains of HAFT and LAFT mice. The P_value is the QTL P_value.

Dataset Information

Name:		12805289
Method:		Microarray and QTL
Tissue:		Whole brain
Phenotype:		Acute functional tolerance to ethanol
Publication:		Tabakoff et al. J Neurosci. (2003) Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors. PubMed
Summary:		We describe a novel approach that uses a combination of selective breeding, quantitative trait locus analysis, and DNA microarray technology to identify candidate genes for the complex phenotype of ethanol tolerance. Tolerance that develops during a single exposure to alcohol is defined as acute functional tolerance (AFT). Lines of mice to display high acute functional tolerance (HAFT mice) and low acute functional tolerance (LAFT mice) to the incoordinating effect of ethanol were used.

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009548.2	NP_033574.2	NC_000077.5 range: 61261943..61267387, complement

Gene Ontology (GO) Annotation