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Gene Information
Gene ID:23157
Symbol:SEPT6
Full Name:septin 6
Alias:KIAA0128|MGC16619|MGC20339|SEP2|SEPT2
Organism:Homo sapiens (Human)
Chromosome:X
Genetic Location:Xq24
Physical Location:118633714-118711360 on NC_000023.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:W25951
Fold Change:-2.21
Dataset Information
Name:15236863
Method:Microarray
Tissue:Prefrontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_015129.5NP_055944.2NC_000023.9 range: 118633714..118711360, complement
NM_145799.3NP_665798.1NC_000023.9 range: 118633714..118711360, complement
NM_145800.3NP_665799.1NC_000023.9 range: 118633714..118711360, complement
NM_145802.3NP_665801.1NC_000023.9 range: 118633714..118711360, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0031105septin complexCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionTAS (11809673)
GO:0005525GTP bindingMolecular FunctionIEA
GO:0005525GTP bindingMolecular FunctionTAS (11809673)
GO:0000910cytokinesisBiological ProcessTAS (11809673)
GO:0007049cell cycleBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:23157
HGNC:15848
Ensembl:ENSG00000125354
MIM:300683
HPRD:06716
HuGE Navigator:23157
dbSNP:SEPT6
GeneCard:SEPT6
AceView:SEPT6