| Gene Information |
| Gene ID: | | 23194 |
| Symbol: | | FBXL7 |
| Full Name: | | F-box and leucine-rich repeat protein 7 |
| Alias: | | FBL6|FBL7 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 5 |
| Genetic Location: | | 5p15.1 |
| Physical Location: | | 15553304-15992899 on NC_000005.8 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | AB020647 | | Fold Change: | | 3.31 |
| | Dataset Information | | Name: | | 15236863 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed | | Summary: | | We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0000151 | ubiquitin ligase complex | Cellular Component | NAS (10531035) | |
| GO:0004842 | ubiquitin-protein ligase activity | Molecular Function | NAS (10531035) | |
| GO:0005515 | protein binding | Molecular Function | IPI (15070733) | |
| GO:0006511 | ubiquitin-dependent protein catabolic process | Biological Process | NAS (10531035) | |
| GO:0006512 | ubiquitin cycle | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 23194 |
| HGNC: | | 13604 |
| Ensembl: | | |
| MIM: | | 605656 |
| HPRD: | | 05740 |
| HuGE Navigator: | | 23194 |
| dbSNP: | | FBXL7 |
| GeneCard: | | FBXL7 |
| AceView: | | FBXL7 |
