ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

P42pop

Full Name:

Myb protein P42POP

Alias:

Myodysa

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 A3

Physical Location:

19576665-19587111 on NC_000073.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 339344 Symbol (Name): LOC339344 (-)

Ortholog Status:

The human GeneID 339344 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		P42pop
Original ID2:		AW047050

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_145579.3	NP_663554.1	NC_000073.5 range: 19576665..19587111

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (15615774)
GO:0003677	DNA binding	Molecular Function	IDA (15615774)
GO:0003700	transcription factor activity	Molecular Function	IDA (15615774)
GO:0005515	protein binding	Molecular Function	IPI (15615774)
GO:0042803	protein homodimerization activity	Molecular Function	IPI (15615774)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (15615774)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (15615774)