ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

DAAM2

Full Name:

dishevelled associated activator of morphogenesis 2

Alias:

KIAA0381|MGC90515|RP1-278E11.1|dJ90A20A.1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

6p21.2

Physical Location:

39868770-39980618 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AB002379
Fold Change:		2.08

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_015345.2	NP_056160.2	NC_000006.10 range: 39868770..39980618

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0003779	actin binding	Molecular Function	IEA
GO:0017048	Rho GTPase binding	Molecular Function	IEA
GO:0016043	cellular component organization and biogenesis	Biological Process	IEA
GO:0030036	actin cytoskeleton organization and biogenesis	Biological Process	IEA