ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

NNT

Full Name:

nicotinamide nucleotide transhydrogenase

Alias:

MGC126502|MGC126503

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

5p13.1-cen

Physical Location:

43638547-43741424 on NC_000005.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 18115 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

NNT

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IEA
GO:0005746	mitochondrial respiratory chain	Cellular Component	TAS (10673423)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0003957	NAD(P)+ transhydrogenase (B-specific) activity	Molecular Function	TAS (9524818)
GO:0051287	NAD binding	Molecular Function	TAS (10673423)
GO:0050661	NADP binding	Molecular Function	IDA (10673423)
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0008750	NAD(P)+ transhydrogenase (AB-specific) activity	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0015992	proton transport	Biological Process	TAS (10673423)
GO:0006099	tricarboxylic acid cycle	Biological Process	TAS (10673423)
GO:0055114	oxidation reduction	Biological Process	TAS (10673423)