ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Snx14

Full Name:

sorting nexin 14

Alias:

B830022K16|C330035N22Rik|YR-14

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 E3.1

Physical Location:

88271612-88333766 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 57231 Symbol (Name): SNX14 (sorting nexin 14)

Ortholog Status:

The human GeneID 57231 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Snx14
Original ID2:		AI839611

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_172926.2	NP_766514.1	NC_000075.5 range: 88271612..88333766, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0004871	signal transducer activity	Molecular Function	RCA (12466851)
GO:0008565	protein transporter activity	Molecular Function	RCA (12466851)
GO:0035091	phosphoinositide binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0007154	cell communication	Biological Process	IEA
GO:0006886	intracellular protein transport	Biological Process	RCA (12466851)
GO:0006810	transport	Biological Process	RCA (12466851)
GO:0015031	protein transport	Biological Process	RCA (12466851)
GO:0007242	intracellular signaling cascade	Biological Process	RCA (12466851)