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Gene Information
Gene ID:24778
Symbol:Slc2a1
Full Name:solute carrier family 2 (facilitated glucose transporter), member 1
Alias:GLUTB|GTG1|Glut1|Gtg3|RATGTG1
Organism:Rattus norvegicus (Rat)
Chromosome:5
Genetic Location:5q36.1
Physical Location:139690800-139719020 on NC_005104.2
Gene Type:protein-coding
Human Ortholog:GeneID: 6513    Symbol (Name): SLC2A1 (solute carrier family 2 (facilitated glucose transporter), member 1)
Ortholog Status:The human GeneID 6513 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Slc2a1
Fold Change:1.15
P Value:0.004
Note:Differential expression between ethanol and water groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_138827.1NP_620182.1NC_005104.2 range: 139690800..139719020
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentISS
GO:0005737cytoplasmCellular ComponentISS
GO:0005737cytoplasmCellular ComponentIEA
GO:0005622intracellularCellular ComponentISS
GO:0005622intracellularCellular ComponentIEA
GO:0005901caveolaCellular ComponentIDA (16419038)
GO:0005911intercellular junctionCellular ComponentIDA (17090404)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentTAS (12399425)
GO:0016323basolateral plasma membraneCellular ComponentIEA
GO:0016323basolateral plasma membraneCellular ComponentISS
GO:0042470melanosomeCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentIEA
GO:0019900kinase bindingMolecular FunctionIPI (16419038)
GO:0005215transporter activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0005351sugar:hydrogen symporter activityMolecular FunctionIEA
GO:0005351sugar:hydrogen symporter activityMolecular FunctionTAS (12399425)
GO:0005355glucose transmembrane transporter activityMolecular FunctionIDA (12006627)
GO:0005355glucose transmembrane transporter activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIDA (10562431)
GO:0005515protein bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (16419038)
GO:0042910xenobiotic transporter activityMolecular FunctionIDA (17064664)
GO:0015758glucose transportBiological ProcessTAS (12399425)
GO:0015758glucose transportBiological ProcessIDA (12006627)
GO:0008643carbohydrate transportBiological ProcessIEA
GO:0006970response to osmotic stressBiological ProcessIEP (12006627)
GO:0042908xenobiotic transportBiological ProcessIDA (17064664)
Other Database Cross Links
NCBI Entrez Gene:24778
RGD:3704
Ensembl:ENSRNOG00000007284
dbSNP:Slc2a1