ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ABL1

Full Name:

c-abl oncogene 1, receptor tyrosine kinase

Alias:

ABL|JTK7|bcr/abl|c-ABL|p150|v-abl

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

9q34.1

Physical Location:

132579088-132752882 on NC_000009.10

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11350 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ABL1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005157.3	NP_005148.2	NC_000009.10 range: 132579088..132752882
NM_007313.2	NP_009297.2	NC_000009.10 range: 132579088..132752882

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	NAS (8242749)
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005730	nucleolus	Cellular Component	IDA (12944467)
GO:0005575	cellular_component	Cellular Component	ND
GO:0008022	protein C-terminus binding	Molecular Function	IPI (11971963)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0030145	manganese ion binding	Molecular Function	IDA (9144171)
GO:0016301	kinase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IDA (9144171)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004715	non-membrane spanning protein tyrosine kinase activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	NAS (8242749)
GO:0003674	molecular_function	Molecular Function	ND
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0000287	magnesium ion binding	Molecular Function	IDA (9144171)
GO:0018108	peptidyl-tyrosine phosphorylation	Biological Process	IDA (9144171)
GO:0030036	actin cytoskeleton organization and biogenesis	Biological Process	ISS
GO:0000115	S-phase-specific transcription in mitotic cell cycle	Biological Process	TAS (8242749)
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	Biological Process	TAS (10391249)
GO:0008150	biological_process	Biological Process	ND
GO:0007155	cell adhesion	Biological Process	IEA
GO:0006464	protein modification process	Biological Process	NAS (8242749)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	TAS (8242749)
GO:0006298	mismatch repair	Biological Process	TAS (10391249)
GO:0051353	positive regulation of oxidoreductase activity	Biological Process	IDA (12893824)