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Gene Information
Gene ID:25282
Symbol:Cox6a1
Full Name:cytochrome c oxidase, subunit VIa, polypeptide 1
Alias:COX6AL
Organism:Rattus norvegicus (Rat)
Chromosome:12
Genetic Location:12q16
Physical Location:42530090-42533143 on NC_005111.2
Gene Type:protein-coding
Human Ortholog:GeneID: 1337    Symbol (Name): COX6A1 (cytochrome c oxidase subunit VIa polypeptide 1)
Ortholog Status:The human GeneID 1337 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Cox6a1
Fold Change:1.13
P Value:0.002
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_012814.1NP_036946.1NC_005111.2 range: 42530090..42533143
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentIEA
GO:0005739mitochondrionCellular ComponentISS
GO:0005740mitochondrial envelopeCellular ComponentIEA
GO:0005743mitochondrial inner membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0004129cytochrome-c oxidase activityMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:25282
RGD:2384
Ensembl:ENSRNOG00000001170
dbSNP:Cox6a1