| Gene Information |
| Gene ID: | | 25621 |
| Symbol: | | Cd81 |
| Full Name: | | CD 81 antigen |
| Alias: | | Tapa1 |
| Organism: | | Rattus norvegicus (Rat) |
| Chromosome: | | 1 |
| Genetic Location: | | 1q41 |
| Physical Location: | | 203327286-203342900 on NC_005100.2 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 975 Symbol (Name): CD81 (CD81 molecule) |
| Ortholog Status: | | The human GeneID 975 is also in human dataset(s). |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | Cd81 | | Fold Change: | | 1.1 | | P Value: | | 0.006 | | Note: | | Differential expression between ethanol and water groups in nucleus accumbens |
| | Dataset Information | | Name: | | 18405950 | | Method: | | Microarray | | Tissue: | | Nucleus accumbens and amygdala | | Phenotype: | | Ethanol self-administration, alcohol-preferring | | Publication: | | Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed | | Summary: | | The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group. |
|
|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016021 | integral to membrane | Cellular Component | IDA (8757260) | |
| GO:0005887 | integral to plasma membrane | Cellular Component | ISS | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0005515 | protein binding | Molecular Function | IPI | |
| GO:0005515 | protein binding | Molecular Function | ISS | |
| GO:0030384 | phosphoinositide metabolic process | Biological Process | ISS | |
| GO:0040008 | regulation of growth | Biological Process | IEP (8757260) | |
| GO:0042127 | regulation of cell proliferation | Biological Process | IDA (11773042) | |
| GO:0043128 | positive regulation of 1-phosphatidylinositol 4-kinase activity | Biological Process | ISS | |
| GO:0000187 | activation of MAPK activity | Biological Process | ISS | |
| GO:0009611 | response to wounding | Biological Process | IEP (8757260) | |
| GO:0008284 | positive regulation of cell proliferation | Biological Process | ISS | |
| GO:0008104 | protein localization | Biological Process | ISS | |
| GO:0006661 | phosphatidylinositol biosynthetic process | Biological Process | ISS | |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | Biological Process | ISS | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 25621 |
| RGD: | | 2315 |
| Ensembl: | | ENSRNOG00000020451 |
| dbSNP: | | Cd81 |
