| Gene Information |
| Gene ID: | | 26047 |
| Symbol: | | CNTNAP2 |
| Full Name: | | contactin associated protein-like 2 |
| Alias: | | CASPR2|CDFE|DKFZp781D1846|NRXN4 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 7 |
| Genetic Location: | | 7q35-q36 |
| Physical Location: | | 145444385-147749018 on NC_000007.12 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | AB020675 | | Fold Change: | | -3.15 |
| | Dataset Information | | Name: | | 15236863 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed | | Summary: | | We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes. |
| | Gene Information | | Original ID1: | | N53741 | | Fold Change: | | 0.69 | | P Value: | | 2.00E-03 | | Tissue: | | Nucleus accumbens |
| | Dataset Information | | Name: | | 15816859 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex and nucleus accumbens | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed | | Summary: | | Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0016021 | integral to membrane | Cellular Component | NAS (11352571) | |
| GO:0005102 | receptor binding | Molecular Function | IEA | |
| GO:0007155 | cell adhesion | Biological Process | IEA | |
| GO:0007165 | signal transduction | Biological Process | IEA | |
| GO:0008038 | neuron recognition | Biological Process | NAS (10624965) | |
| GO:0019226 | transmission of nerve impulse | Biological Process | NAS (11352571) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 26047 |
| HGNC: | | 13830 |
| Ensembl: | | ENSG00000174469 |
| MIM: | | 604569 |
| HPRD: | | 05197 |
| HuGE Navigator: | | 26047 |
| dbSNP: | | CNTNAP2 |
| GeneCard: | | CNTNAP2 |
| AceView: | | CNTNAP2 |
