ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Rpl3

Full Name:

ribosomal protein L3

Alias:

F2|J1|MGC103388

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E1

Physical Location:

79908224-79913764 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6122 Symbol (Name): RPL3 (ribosomal protein L3)

Ortholog Status:

The human GeneID 6122 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Rpl3
Original ID2:		Y00225

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013762.1	NP_038790.1	NC_000081.5 range: 79908224..79913764, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005840	ribosome	Cellular Component	IEA
GO:0030529	ribonucleoprotein complex	Cellular Component	IEA
GO:0003735	structural constituent of ribosome	Molecular Function	IEA
GO:0006412	translation	Biological Process	IEA