ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mrpl17

Full Name:

mitochondrial ribosomal protein L17

Alias:

MRP-L26|Rpml26

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 F1

Physical Location:

112952295-112959600 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 63875 Symbol (Name): MRPL17 (mitochondrial ribosomal protein L17)

Ortholog Status:

The human GeneID 63875 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Mrpl17
Original ID2:		AI843081

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025301.2	NP_079577.1	NC_000073.5 range: 112952295..112959600, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	RCA (12466851)
GO:0005739	mitochondrion	Cellular Component	IEA
GO:0005743	mitochondrial inner membrane	Cellular Component	IDA (12865426)
GO:0005762	mitochondrial large ribosomal subunit	Cellular Component	ISS (10593885)
GO:0005840	ribosome	Cellular Component	RCA (12466851)
GO:0030529	ribonucleoprotein complex	Cellular Component	IEA
GO:0003735	structural constituent of ribosome	Molecular Function	ISS (10593885)
GO:0000002	mitochondrial genome maintenance	Biological Process	TAS (10593885)
GO:0006412	translation	Biological Process	ISS (10593885)