| Gene Information |
| Gene ID: | | 286932 |
| Symbol: | | Vps54 |
| Full Name: | | vacuolar protein sorting 54 (yeast) |
| Alias: | | Vsp54 |
| Organism: | | Rattus norvegicus (Rat) |
| Chromosome: | | 14 |
| Genetic Location: | | 14q22 |
| Physical Location: | | 102018123-102072257 on NC_005113.2 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 51542 Symbol (Name): VPS54 (vacuolar protein sorting 54 homolog (S. cerevisiae)) |
| Ortholog Status: | | The human GeneID 51542 is not in current human dataset. |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | Vps54 | | Fold Change: | | -1.15 | | P Value: | | 0.008 | | Note: | | Differential expression between ethanol and saccharin groups in amygdala |
| | Dataset Information | | Name: | | 18405950 | | Method: | | Microarray | | Tissue: | | Nucleus accumbens and amygdala | | Phenotype: | | Ethanol self-administration, alcohol-preferring | | Publication: | | Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed | | Summary: | | The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group. |
|
|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0015031 | protein transport | Biological Process | IEA | |
| GO:0040007 | growth | Biological Process | ISS | |
| GO:0042147 | retrograde transport, endosome to Golgi | Biological Process | IEA | |
| GO:0048873 | homeostasis of number of cells within a tissue | Biological Process | ISS | |
| GO:0050881 | musculoskeletal movement | Biological Process | ISS | |
| GO:0060052 | neurofilament cytoskeleton organization and biogenesis | Biological Process | ISS | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 286932 |
| RGD: | | 628718 |
| Ensembl: | | ENSRNOG00000007125 |
| dbSNP: | | Vps54 |
