ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

GPX1

Full Name:

glutathione peroxidase 1

Alias:

GSHPX1|MGC14399|MGC88245

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3p21.3

Physical Location:

49369612-49370794 on NC_000003.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 14775 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

GPX1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005829	cytosol	Cellular Component	EXP (8428933)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005739	mitochondrion	Cellular Component	IDA (10833429)
GO:0008430	selenium binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0043295	glutathione binding	Molecular Function	IC (12829378)
GO:0017124	SH3 domain binding	Molecular Function	IPI (12893824)
GO:0004602	glutathione peroxidase activity	Molecular Function	IEA
GO:0004602	glutathione peroxidase activity	Molecular Function	EXP (8428933)
GO:0008539	proteasome inhibitor activity	Molecular Function	IDA (12751788)
GO:0033599	regulation of mammary gland epithelial cell proliferation	Biological Process	IMP (16945136)
GO:0040029	regulation of gene expression, epigenetic	Biological Process	IDA (16132718)
GO:0042744	hydrogen peroxide catabolic process	Biological Process	IDA (15203190)
GO:0043154	negative regulation of caspase activity	Biological Process	IMP (12221075)
GO:0001836	release of cytochrome c from mitochondria	Biological Process	IMP (12221075)
GO:0030503	regulation of cell redox homeostasis	Biological Process	IDA (12829378)
GO:0010269	response to selenium ion	Biological Process	IMP (12810669)
GO:0009650	UV protection	Biological Process	IMP (17097614)
GO:0006979	response to oxidative stress	Biological Process	IEA
GO:0006916	anti-apoptosis	Biological Process	IMP (12221075)
GO:0006749	glutathione metabolic process	Biological Process	IDA (12829378)
GO:0060047	heart contraction	Biological Process	IMP (14573732)