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Gene Information
Gene ID:2885
Symbol:GRB2
Full Name:growth factor receptor-bound protein 2
Alias:ASH|EGFRBP-GRB2|Grb3-3|MST084|MSTP084
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q24-q25
Physical Location:70825751-70913384 on NC_000017.9, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 14784 Rat: 81504 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:GRB2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002086.4NP_002077.1NC_000017.9 range: 70825751..70913384, complement
NM_203506.2NP_987102.1NC_000017.9 range: 70825751..70913384, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0005829cytosolCellular ComponentEXP (7739560|8479541|8493579|8621719|8810325|9356464|9690470|10567358|10648629|10734310|10913131|11606067)
GO:0005829cytosolCellular ComponentTAS (14722116)
GO:0005070SH3/SH2 adaptor activityMolecular FunctionTAS (8253073)
GO:0043560insulin receptor substrate bindingMolecular FunctionIPI (8388384)
GO:0005154epidermal growth factor receptor bindingMolecular FunctionIPI (12577067)
GO:0007265Ras protein signal transductionBiological ProcessEXP (11520933)
GO:0007265Ras protein signal transductionBiological ProcessTAS (8253073)
GO:0007267cell-cell signalingBiological ProcessTAS (8253073)
GO:0008286insulin receptor signaling pathwayBiological ProcessIPI (8388384)
GO:0007173epidermal growth factor receptor signaling pathwayBiological ProcessTAS (1322798)
Other Database Cross Links
NCBI Entrez Gene:2885
HGNC:4566
Ensembl:ENSG00000177885
MIM:108355
HPRD:00150
HuGE Navigator:2885
dbSNP:GRB2
GeneCard:GRB2
AceView:GRB2