ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

GRIK2

Full Name:

glutamate receptor, ionotropic, kainate 2

Alias:

EAA4|GLR6|GLUK6|GLUR6|MGC74427|MRT6

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

6q16.3-q21

Physical Location:

101953674-102623473 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 14806 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

GRIK2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045211	postsynaptic membrane	Cellular Component	IEA
GO:0045202	synapse	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0005887	integral to plasma membrane	Cellular Component	TAS (7536611)
GO:0030054	cell junction	Cellular Component	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0015277	kainate selective glutamate receptor activity	Molecular Function	IDA (15537878)
GO:0005234	extracellular-glutamate-gated ion channel activity	Molecular Function	IEA
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0007215	glutamate signaling pathway	Biological Process	TAS (7536611)
GO:0006811	ion transport	Biological Process	IEA
GO:0031557	induction of programmed cell death in response to chemical stimulus	Biological Process	NAS (15537878)
GO:0048172	regulation of short-term neuronal synaptic plasticity	Biological Process	IMP (15537878)
GO:0050806	positive regulation of synaptic transmission	Biological Process	IMP (15537878)
GO:0051402	neuron apoptosis	Biological Process	IDA (15537878)