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Gene Information
Gene ID:29464
Full Name:solute carrier family 6 (neurotransmitter transporter, taurine), member 6
Organism:Rattus norvegicus (Rat)
Genetic Location:4q34
Physical Location:125875816-125945794 on NC_005103.2
Gene Type:protein-coding
Human Ortholog:GeneID: 6533    Symbol (Name): SLC6A6 (solute carrier family 6 (neurotransmitter transporter, taurine), member 6)
Ortholog Status:The human GeneID 6533 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Slc6a6
Fold Change:-1.48
P Value:0.0001
Gene Information
Original ID1:Slc6a6
Fold Change:-1.35
P Value:0.0021
Tissue:Frontal cortex
Dataset Information
Method:Microarray and QTL
Tissue:Nucleus accumbens, frontal cortex, amygdala, hippocampus, and striatum
Phenotype:Alcohol Preference, alcohol-preferring, alcohol-nonpreferring
Publication:Carr et al. Alcohol Clin Exp Res. (2007) Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. PubMed
Summary:A highly significant quantitative trait locus (QTL) on chromosome 4 that influenced alcohol preference was identified by analyzing crosses between the iP (inbred alcohol-preferring) and iNP (inbred alcohol-nonpreferring) rats. Congenic strains in which the iP chromosome 4 QTL interval was transferred to the iNP (NP.P) exhibited the expected increase in alcohol consumption compared with the iNP background strain. Analyses within individual brain regions that focused on genes within the QTL interval detected differential expression in all 5 brain regions; a total of 35 genes were detected in at least 1 region, ranging from 6 genes in the nucleus accumbens to 22 in the frontal cortex.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017206.1NP_058902.1NC_005103.2 range: 125875816..125945794
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentIEA
GO:0001761beta-alanine transmembrane transporter activityMolecular FunctionISS
GO:0015293symporter activityMolecular FunctionIEA
GO:0030977taurine bindingMolecular FunctionIDA (1435737)
GO:0005369taurine:sodium symporter activityMolecular FunctionIEA
GO:0005369taurine:sodium symporter activityMolecular FunctionIDA (1435737)
GO:0005368taurine transmembrane transporter activityMolecular FunctionISS
GO:0015734taurine transportBiological ProcessIEA
GO:0015734taurine transportBiological ProcessIMP (1435737)
GO:0015734taurine transportBiological ProcessISS
GO:0001762beta-alanine transportBiological ProcessISS
GO:0006836neurotransmitter transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:29464