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Gene Information
Gene ID:29547
Symbol:Homer2
Full Name:homer homolog 2 (Drosophila)
Alias:Vesl-2
Organism:Rattus norvegicus (Rat)
Chromosome:1
Genetic Location:1q31
Physical Location:137827127-137933088 on NC_005100.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 9455    Symbol (Name): HOMER2 (homer homolog 2 (Drosophila))
Ortholog Status:The human GeneID 9455 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Homer2
Fold Change:-1.16
P Value:0.008
Note:Differential expression between ethanol and water groups in amygdala
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_053309.1NP_445761.1NC_005100.2 range: 137827127..137933088, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentISS
GO:0003779actin bindingMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionISS
GO:0030160GKAP/Homer scaffold activityMolecular FunctionISS
Other Database Cross Links
NCBI Entrez Gene:29547
RGD:620705
Ensembl:ENSRNOG00000019297
dbSNP:Homer2