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Gene Information
Gene ID:296966
Symbol:Chchd3
Full Name:coiled-coil-helix-coiled-coil-helix domain containing 3
Organism:Rattus norvegicus (Rat)
Chromosome:4
Genetic Location:4q22
Physical Location:59891616-60177213 on NC_005103.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 54927    Symbol (Name): CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3)
Ortholog Status:The human GeneID 54927 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Chchd3
Fold Change:-1.15
P Value:0.0041
Tissue:Frontal cortex
Gene Information
Original ID1:Chchd3
Fold Change:-1.16
P Value:0.0035
Tissue:Striatum
Dataset Information
Name:17451403
Method:Microarray and QTL
Tissue:Nucleus accumbens, frontal cortex, amygdala, hippocampus, and striatum
Phenotype:Alcohol Preference, alcohol-preferring, alcohol-nonpreferring
Publication:Carr et al. Alcohol Clin Exp Res. (2007) Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. PubMed
Summary:A highly significant quantitative trait locus (QTL) on chromosome 4 that influenced alcohol preference was identified by analyzing crosses between the iP (inbred alcohol-preferring) and iNP (inbred alcohol-nonpreferring) rats. Congenic strains in which the iP chromosome 4 QTL interval was transferred to the iNP (NP.P) exhibited the expected increase in alcohol consumption compared with the iNP background strain. Analyses within individual brain regions that focused on genes within the QTL interval detected differential expression in all 5 brain regions; a total of 35 genes were detected in at least 1 region, ranging from 6 genes in the nucleus accumbens to 22 in the frontal cortex.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_238346.4XP_238346.4NC_005103.2 range: 59891616..60177213, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentISS
GO:0005743mitochondrial inner membraneCellular ComponentISS
GO:0005515protein bindingMolecular FunctionISS
Other Database Cross Links
NCBI Entrez Gene:296966
RGD:1310325
Ensembl:ENSRNOG00000013211
dbSNP:Chchd3