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Gene Information
Gene ID:296973
Full Name:2,3-bisphosphoglycerate mutase
Organism:Rattus norvegicus (Rat)
Genetic Location:4q22
Physical Location:61858883-61888006 on NC_005103.2
Gene Type:protein-coding
Human Ortholog:GeneID: 669    Symbol (Name): BPGM (2,3-bisphosphoglycerate mutase)
Ortholog Status:The human GeneID 669 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Bpgm
Fold Change:1.16
P Value:0.0004
Tissue:Frontal cortex
Dataset Information
Method:Microarray and QTL
Tissue:Nucleus accumbens, frontal cortex, amygdala, hippocampus, and striatum
Phenotype:Alcohol Preference, alcohol-preferring, alcohol-nonpreferring
Publication:Carr et al. Alcohol Clin Exp Res. (2007) Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. PubMed
Summary:A highly significant quantitative trait locus (QTL) on chromosome 4 that influenced alcohol preference was identified by analyzing crosses between the iP (inbred alcohol-preferring) and iNP (inbred alcohol-nonpreferring) rats. Congenic strains in which the iP chromosome 4 QTL interval was transferred to the iNP (NP.P) exhibited the expected increase in alcohol consumption compared with the iNP background strain. Analyses within individual brain regions that focused on genes within the QTL interval detected differential expression in all 5 brain regions; a total of 35 genes were detected in at least 1 region, ranging from 6 genes in the nucleus accumbens to 22 in the frontal cortex.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_199382.1NP_955414.1NC_005103.2 range: 61858883..61888006
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0003674molecular_functionMolecular FunctionND
GO:0003824catalytic activityMolecular FunctionIEA
GO:0016868intramolecular transferase activity, phosphotransferasesMolecular FunctionIEA
GO:0006096glycolysisBiological ProcessIEA
GO:0008152metabolic processBiological ProcessIEA
GO:0048821erythrocyte developmentBiological ProcessIDA (6097373)
Other Database Cross Links
NCBI Entrez Gene:296973