ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Hip1r

Full Name:

huntingtin interacting protein 1 related

Alias:

AA410023|mKIAA0655

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

5 F

Physical Location:

124423647-124453208 on NC_000071.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9026 Symbol (Name): HIP1R (huntingtin interacting protein 1 related)

Ortholog Status:

The human GeneID 9026 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Hip1r
Original ID2:		AI846182

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_145070.2	NP_659507.2	NC_000071.5 range: 124423647..124453208

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005856	cytoskeleton	Cellular Component	IDA (10613908)
GO:0005905	coated pit	Cellular Component	IDA (10613908)
GO:0016020	membrane	Cellular Component	IEA
GO:0003779	actin binding	Molecular Function	IDA (10613908)
GO:0005543	phospholipid binding	Molecular Function	IEA
GO:0006898	receptor-mediated endocytosis	Biological Process	IDA (10613908)